牡荆(Vitex negundo var.cannabi- folia)属马鞭草科(Verbenaceae)植物。江西上饶地区医科所用牡荆子脱脂后的95%乙醇提取部分进行药理筛选。确定了平喘的有效部位牡荆子Ⅰ号。该部位已临床验证了300余例,总有效率80%以上,显效率50%。我们采用硅胶柱层析方法,以氯仿、甲醇进行梯度洗脱,从中分离到三个化合物。经紫外、红外、质谱、及核磁共振谱分析,确定为丁香酸(syringic acid)、香草酸 Vitex negundo var. cannabi-folia is a Verbenaceae plant. The pharmacological screening of 95% ethanol extracts from Vitex negundo seedlings was carried out in the Shangrao district of Jiangxi. Identified the effective site of asthma, Vitex I. The site has been clinically verified more than 300 cases, the total efficiency of more than 80%, significant efficiency of 50%. We used silica gel column chromatography with a gradient elution of chloroform and methanol to isolate three compounds. By ultraviolet, infrared, mass spectrometry, and nuclear magnetic resonance spectroscopy, identified as syringic acid, vanillic acid