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临床上应用抗生素治疗感染性疾病已有50余年了。目前围手术期间应用抗生素预防感染已被提高到较重要的地位,在减少手术手感染性并发症方面有很重要的作用。围手术期应用抗生素不仅可预防由于手术带来的感染,还可预防非外科性感染如肺炎等。预期感染率超过50％的手术都应应用抗生素预防感染。肿瘤外科中食管癌、胃痛、大肠癌、胆囊癌术后感染率较高,因此预防性使用抗生素对于免疫力低下的肿瘤病人来说显得更为重要。一、肿瘤病人的特点正常免疫机制的破坏可能是肿瘤发生的一个重要因素,而肿瘤的逐步发展亦使机体的免疫功能进
Clinical antibiotic treatment of infectious diseases has been more than 50 years. At present, the use of antibiotics to prevent infection during the perioperative period has been promoted to a more important position, and it has a very important role in reducing surgical hand infection complications. Perioperative antibiotics not only prevent infections caused by surgery, but also prevent non-surgical infections such as pneumonia. Surgery with an expected infection rate of more than 50% should use antibiotics to prevent infection. The incidence of esophageal cancer, stomach pain, colorectal cancer, and gallbladder cancer in tumor surgery is high, so the use of antibiotic prophylaxis is even more important for immunocompromised tumor patients. First, the characteristics of cancer patients The destruction of normal immune mechanisms may be an important factor in tumor development, and the gradual development of tumors also makes the body’s immune function into