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β_2~-酝微球蛋白(β_2~-microglobulin,简称β_2~-—MG)升高与肿瘤的发生发展有关。本文对21例膀胱癌患者的血清β_2—MG水平进行了检查分析,并就血清β_2—MG在膀胱癌诊断中的价值作一简要讨论。 材料与方法 病例:从1990年9月至1991年12月间收集膀胱癌21例,男16例,女5例,平均年龄63.4岁。全部病例均经病理学检查确诊,均为移行上皮癌,其中Ⅰ级7例、 Ⅱ级8例、Ⅲ级4例、Ⅳ级2例。对照组为其他泌尿系疾病患者(不包括尿毒症患者)20例。 测定方法:于手术前及术后两周抽取患者静脉血标本,采用中国原子能研究院提供的~(125)Ⅰ—β_2—MG放免盒测定。
β_2 ~ --microglobulin (β_2 ~ -microglobulin, referred to as β_2 ~ - MG) increased with the occurrence and development of the tumor. In this paper, 21 cases of bladder cancer serum β_2-MG levels were examined and analyzed, and serum β_2-MG in the diagnosis of bladder cancer for a brief discussion. Materials and Methods Case: 21 cases of bladder cancer were collected from September 1990 to December 1991 with 16 males and 5 females, with an average age of 63.4 years. All cases were diagnosed by pathological examination, all of which were transitional epithelial carcinomas, including grade Ⅰ in 7 cases, grade Ⅱ in 8 cases, grade Ⅲ in 4 cases and grade Ⅳ in 2 cases. Control group for other urological diseases (excluding uremia patients) 20 cases. Assay Methods: venous blood samples were taken before surgery and two weeks after the operation, using 125I-β_2-MG radioimmunoassay kit provided by China Institute of Atomic Energy.