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为了解佝偻病患儿的体液免疫状况,我科门诊于1992年对97例6个月～7岁佝偻病患儿进行了免疫球蛋白单项观察,并以同龄健康儿为对照组。结果发现,观察组6个月～1岁组,1岁～3岁组IgA,5～7岁组IgM与对照组无显著差异。而6个月～1岁,1岁～3岁组患儿的血清IgG水平明显低于对照组(P<0.01)。提示:佝偻病患儿的体液免疫缺陷主要表现在3岁以前,并以IgG水平降低为主,这可能与该年龄组患儿多处于佝偻病初期或激期有关。
To understand the humoral immune status of children with rickets, our clinic conducted single immunoglobulin observation in 97 children with rickets aged 6 months to 7 years in 1992 and healthy children of the same age as the control group. The results showed that the observation group 6 months to 1 year old group, 1 year old to 3 years old group IgA, 5 to 7 years old group IgM no significant difference with the control group. Serum IgG levels in children aged 6 months to 1 year and 1 year to 3 years old were significantly lower than those in the control group (P <0.01). Hint: The humoral immune deficiency in children with rickets was mainly manifested by the age of 3 years, with the decrease of IgG level, which may be related to the multiple rickets patients in this age group in the early or rickets.