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目的探讨24h动态血压监测对老年糖尿病自主神经病变的影响。方法选择2011年1月~2013年1月我科所收治的40例老年糖尿病患者,本组全部患者在监测前一周都不得再服用那些会对血压造成影响的药物,对血压进行常规测量,分别计算各组血压负荷值参数、最低24h DBP、SBP及最高24h DBP、SBP。结果 13例中高危险水平组的最高血压SBP为(165.8±13.1)mmHg,最高血压DBP为(98.9±8.4)mmHg,最低血压SBP为(115.7±17.3)mmHg,最低血压DBP为(76.3±10.6)mmHg。17例低危险水平组的最高血压SBP为(143.8±23.3)mmHg,最高血压DBP为(85.4±8.2)mmHg,最低血压SBP为(101.4±17.3)mmHg,最低血压DBP为(61.3±6.6)mmHg。10例正常组的最高血压SBP为(135.4±26.2)mmHg,最高血压DBP为(71.4±11.1)mmHg,最低血压SBP为(87.4±7.3)mmHg,最低血压DBP为(50.4±9.0)mmHg,具有较大的差异。结论对24h动态血压监测对老年糖尿病自主神经病变的影响进行研究,可以明显地看出,糖尿病患者是否合并自主神经病变与血压昼夜节律改变存在着较大的关系。
Objective To investigate the effect of 24h ambulatory blood pressure monitoring on senile diabetic autonomic neuropathy. Methods From January 2011 to January 2013, 40 cases of elderly patients with diabetes mellitus were enrolled in our department. All patients in this group were prohibited from taking any medication that would affect blood pressure a week before the monitoring. The blood pressure was measured routinely Blood pressure load parameters of each group were calculated, the lowest 24h DBP, SBP and the highest 24h DBP, SBP. Results The highest SBP was (165.8 ± 13.1) mmHg, the highest DBP was (98.9 ± 8.4) mmHg, the lowest SBP was (115.7 ± 17.3) mmHg, the lowest DBP was (76.3 ± 10.6) mmHg. The SBP of the lowest risk group was (143.8 ± 23.3) mmHg, the highest DBP was (85.4 ± 8.2) mmHg, the lowest SBP was (101.4 ± 17.3) mmHg and the lowest BPP was (61.3 ± 6.6) mmHg . The highest SBP was (135.4 ± 26.2) mmHg, the highest BPP was (71.4 ± 11.1) mmHg, the lowest SBP was (87.4 ± 7.3) mmHg and the lowest BPP was (50.4 ± 9.0) mmHg in 10 normal subjects Big difference. Conclusions The influence of 24-h ambulatory blood pressure monitoring on senile diabetic autonomic neuropathy was studied. It can be clearly seen that there is a significant relationship between diabetic autonomic neuropathy and changes of circadian rhythm of blood pressure.