动脉粥样硬化(AS)发生过程起始于LDL-C在内膜下的堆积,内皮细胞的激活以及单核细胞和T淋巴细胞的募集,促进炎症反应;单核细胞分化成巨噬细胞,吞噬经修饰的脂蛋白,最后成为泡沫细胞;斑块中的T细胞识别该区域的抗原,上调Th1反应,诱发局部的炎症反应,使斑块增大;炎症反应激活引起 The process of atherosclerosis (AS) starts from the accumulation of LDL-C in the intima, the activation of endothelial cells and the recruitment of monocytes and T lymphocytes to promote the inflammatory response; monocytes differentiate into macrophages, Phagocytic modified lipoprotein, and finally become foam cells; T cells in the plaque recognize the antigen in the region, up-regulation of Th1 response, inducing local inflammatory response, the plaque increases; activation of the inflammatory response caused