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我们采用聚合酶链反应-单链构象多态性(PCR-SSCP)技术,对p53基因突变情况进行检测和分析,以探讨EBV与p53基因突变的关系。1 材料与方法标本:21例鼻咽癌活检组织来自本院耳鼻咽喉科,全部患者未接受过放射治疗。病理检查均为低分化鳞状细胞癌。以5?
We used polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technology, p53 gene mutation detection and analysis to explore EBV and p53 gene mutation. 1 Materials and Methods Specimens: 21 cases of nasopharyngeal carcinoma biopsy tissue from otolaryngology hospital, all patients have not received radiation therapy. Pathological examination were poorly differentiated squamous cell carcinoma. With 5?