我们观察94例脑肿瘤中,41例伴有一定的皮肤改变,虽然大多数是非特异性的。但鼻孔搔痒、足底水疤有其特异性,值得重视。色素增加,掌蹠及甲皱襞过度角化现象其发生率亦较高,决非偶然巧合。如能进一步观察研究,这不但对脑肿瘤病情的判断有所帮助,对皮肤色素病变及表皮角化机制的研究亦有裨益。 Of the 94 brain tumors we observed, 41 were associated with certain skin changes, although most were non-specific. However, the nostrils and foot blisters have specificity and deserve attention. The increase in pigmentation, and the occurrence of hyperkeratosis in palmoplantar and crustular folds are also high. It is by no means coincidental. If we can further observe and study, this will not only help judge the condition of brain tumor, but also benefit the study of skin pigmentation and epidermal keratinization.