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目的了解药品不良反应(ADR)发生的特点及一般规律。方法对本院2011年1至10月临床各科呈报的ADR病例分别从患者年龄、给药途径、药品种类、累及器官或系统及临床表现等方面进行统计、分析。结果大于60岁的患者ADR发生率较高(43.2%);静脉滴注给药引发的ADR占94.4%;中药制剂的ADR报告例数居第1位(29.6%)。主要临床表现为皮肤及其附件损害(31.2%)。结论开展ADR监测工作是医疗机构的重要任务,加强ADR监测、报告、诊断和处理对确保安全用药至关重要。
Objective To understand the characteristics and general rules of adverse drug reaction (ADR). Methods The ADR cases reported in clinical departments from January to October in 2011 were statistically analyzed from the aspects of patient’s age, route of administration, type of drug, organs involved or system and clinical manifestation. Results The incidence of ADR was higher in patients older than 60 years old (43.2%). ADR caused by intravenous drip infusion accounted for 94.4%. The number of ADR cases reported in Chinese medicine was the first (29.6%). The main clinical manifestations of damage to the skin and its accessories (31.2%). Conclusion It is an important task for medical institutions to carry out ADR monitoring. To strengthen the monitoring, reporting, diagnosis and treatment of ADR is essential for ensuring safe medication.