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目的:探讨原发性肝恶性肿瘤患者凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)指标变化的临床诊断价值。方法:采集126例原发性肝恶性肿瘤患者和80例正常健康体检者的外周血,检测其PT、APTT、FIB的表达水平并进行对比分析。结果:原发性肝恶性肿瘤PT、APTT结果增高,各组与对照组比较均有统计学意义(P<0.05);FIB除肝癌合并丙肝组与对照组比较差异无统计学意义(P>0.05),其他组与对照组比较差异均有统计学意义(P<0.05)。结论:检测原发性肝恶性肿瘤患者的PT、APTT、FIB的表达有助于辅助诊断肝脏损伤程度及评估预后。
Objective: To investigate the clinical diagnostic value of prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen (FIB) in patients with primary liver cancer. Methods: Peripheral blood of 126 patients with primary liver cancer and 80 healthy controls were collected and their PT, APTT and FIB expression levels were detected and compared. Results: The results of PT and APTT in primary hepatic malignancies were significantly higher than those in control group (P <0.05). There was no significant difference between FIB group and control group (P> 0.05) ), The other groups were significantly different from the control group (P <0.05). Conclusion: Detecting the expression of PT, APTT and FIB in patients with primary hepatic malignancies is helpful to diagnose the degree of liver injury and evaluate the prognosis.