手足口病(HFMD)是一种常见的传染病,可引起四肢及口腔等部位的皮疹及疱疹〔1〕。2008年以来,我国多个省份大规模暴发手足口病,并有死亡病例的报道,我国卫计委于2008年5月2日将其列为丙类传染病。引发手足口病的肠道病毒有20多种,其中以肠道病毒71型(EV71)和柯萨奇病毒A组16型(Cox A16)最为常见〔2〕。手足口病患儿病情多数轻微,少数可出现中枢神经系统和呼吸系统损害, Hand, foot and mouth disease (HFMD) is a common infectious disease that causes rashes and herpes in parts of the mouth and mouth [1]. Since 2008, large-scale outbreaks of hand-foot-mouth disease have been reported in many provinces of China and there are reports of deaths. The SPS Committee of China named it as Category C infectious disease on May 2, 2008. There are more than 20 kinds of enterovirus causing hand-foot-mouth disease, among which enterovirus 71 (EV71) and Cox-A16 (type Cox A16) are the most common [2]. Hand, foot and mouth disease in children with mild disease, a few may appear in the central nervous system and respiratory system damage,