论文部分内容阅读
目的:探讨铁皮石斛精粉治疗急性有机磷中毒患者解毒及其抗氧化的临床疗效。方法:对29例急性有机磷中毒患者在常规治疗的基础上,用铁皮石斛精粉口服,每天3次,连用3天,观察乙酰胆碱酯酶(Ach E)、超氧化物歧化酶(SOD)和丙二醛(MDA)水平,并与29例常规治疗组比较。结果:治疗前两组Ach E水平明显低于健康组,治疗后两组Ach E水平均有明显升高,治疗组升高的幅度较对照组大,治疗前两组SOD水平低于健康组,MDA水平高于健康组,治疗后治疗组SOD和MDA与健康组比较差异无统计学意义。结论:铁皮石斛可提高患者的耐中毒能力,改善患者的胆碱能代谢紊乱和氧化应激功能紊乱,对减轻患者的中毒症状,减少并发症的发生,促进康复等有益。
Objective: To investigate the detoxification and anti-oxidation clinical efficacy of Dendrobium candidum in the treatment of patients with acute organophosphate poisoning. Methods: A total of 29 patients with acute organophosphate poisoning were treated with oral administration of Dendrobium officinale powder three times a day for 3 consecutive days. The levels of acetylcholinesterase (AchE), superoxide dismutase (SOD) and Malondialdehyde (MDA) levels were compared with 29 routine treatment groups. Results: The levels of Ach E in the two groups before treatment were significantly lower than those in the healthy group. The levels of Ach E in the two groups were significantly increased after treatment. The increase in the treatment group was larger than that in the control group. The levels of SOD in the two groups before treatment were lower than those in the healthy group MDA level was higher than that of healthy group. There was no significant difference in SOD and MDA between treatment group and healthy group after treatment. Conclusion: Dendrobium candidum can improve the patient’s tolerance to poisoning, improve cholinergic metabolism disorders and oxidative stress disorder in patients, alleviate the symptoms of poisoning, reduce the incidence of complications and promote rehabilitation.