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目的观察评价使用坎地沙坦对慢性心功能衰竭患者心功能的治疗作用。方法选择慢性心力衰竭患者60例,随机分为两组,对照组使用卡托普利及地高辛等,治疗组加用坎地沙坦。对治疗前后两组间使用条件、临床资料进行比较分析。结果治疗组和对照组总有效率分别为87.6%和75.1%,两组比较差异无统计学意义(P>0.05)。治疗组心功能NYHA分级好转率优于对照组(P<0.05);左室舒张末期内径(LVDD)缩小(P<0.01),左室射血分数(LVEF)增加(P<0.05),与对照组比较差异有统计学意义。结论用坎地沙坦治疗慢性心功能衰竭明显优于常规治疗,可以改善心力衰竭患者临床症状。
Objective To evaluate the therapeutic effect of candesartan on cardiac function in patients with chronic heart failure. Methods Sixty patients with chronic heart failure were randomly divided into two groups. The control group received captopril and digoxin, and the treatment group received candesartan. The treatment conditions before and after the use of the two groups, clinical data were analyzed. Results The total effective rates of the treatment group and the control group were 87.6% and 75.1%, respectively, with no significant difference between the two groups (P> 0.05). The improvement rate of cardiac function NYHA grading in the treatment group was better than that in the control group (P <0.05); the left ventricular end-diastolic diameter (LVDD) and the left ventricular ejection fraction (LVEF) The difference between the two groups was statistically significant. Conclusion Candesartan in treatment of chronic heart failure was significantly better than conventional treatment, can improve the clinical symptoms of patients with heart failure.