血清铁蛋白(SF)是一种贮存铁的蛋白质,许多恶性实体肿瘤患者 SF 增高。SF 对恶性肿瘤诊断、预后估计有重要作用。笔者用放射免疫法测定小儿恶性实体肿瘤 SF,以探讨其临床意义。材料与方法:恶性肿瘤组20例(神经母细胞瘤14例,肾母细胞瘤4例,恶性畸胎瘤2例),良性肿瘤组20例(良性畸胎瘤6例,神经节细胞瘤3例,淋巴管瘤6例,血管瘤5例),对照组40例(正常儿童)。三组年龄均为3个月至6岁,均排除铁剂影响。肿瘤均经病理证实。 Serum ferritin (SF) is an iron-storing protein that is elevated in many patients with malignant solid tumors. SF has an important role in the diagnosis and prognosis of malignant tumors. The author used radioimmunoassay to detect malignant solid tumors in children SF to explore its clinical significance. MATERIALS AND METHODS: Twenty patients with malignant tumor (neuroblastoma 14, nephroblastoma 2, malignant teratoma 2), benign tumor 20 (benign teratoma 6, ganglioneuroma 3 Cases, lymphangioma in 6 cases, hemangioma in 5 cases), control group of 40 cases (normal children). The three groups were all 3 months to 6 years old, all excluding iron effects. Tumors were confirmed by pathology.