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目的观察曲美他嗪治疗冠心病稳定型心绞痛临床疗效。方法对45例稳定型心绞痛患者在常规治疗的基础上加用曲美他嗪60mg/d,治疗8周后观察临床疗效和心电图变化。结果有效率达91.1%,明显优于常规组(P<0.05),并可明显减少心绞痛发作次数、减少硝酸甘油的用量,显著回升下移的心电图ST段和缩短心肌缺血时间(P<0.05),且无明显不良反应。结论稳定型心绞痛患者在常规治疗的基础上加用曲美他治疗是安全有效,值得临床推广应用。
Objective To observe the clinical efficacy of trimetazidine in the treatment of stable angina pectoris of coronary heart disease. Methods 45 patients with stable angina pectoris were treated with trimetazidine 60mg / d on the basis of routine treatment. The curative effect and electrocardiogram changes were observed after 8 weeks of treatment. Results The effective rate was 91.1%, which was significantly better than that of the conventional group (P <0.05). It also significantly reduced the number of angina pectoris attacks, decreased the dosage of nitroglycerin, significantly reversed the ST segment depression and shortened the myocardial ischemia time ), And no obvious adverse reactions. Conclusion Patients with stable angina pectoris treated with trimetazidine based on routine treatment are safe and effective, which is worthy of clinical application.