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目的探讨加强血液灌流在误服毒鼠强(四亚甲基二砜四氨)患儿救治中的临床应用效果,总结干预方法。方法纳入2010年1月—2015年1月误服毒鼠强中毒的患儿,其中观察组给予加强血液灌流治疗(n=45),对照组给予常规血液灌流(n=45),并分别搜集临床资料进行分析。结果对照组45例,其中男23例,女22例;平均年龄(4.75±2.68)岁;治愈36例,死亡9例;患儿抽搐停止时间(3.96±1.14)d;住院时间(11.7±3.5)d。观察组男24例,女21例;平均年龄(4.58±2.24)岁;45例均治愈,无死亡病例;抽搐时间(1.83±0.57)d;住院时间(7.8±2.1)d。结论通过股静脉进行加强血液灌流能显著降低毒鼠强中毒患儿病死率,缩短抽搐时间、住院时间。
Objective To investigate the clinical application of hemoperfusion in the treatment of children with tetramine (tetramethylsulfone tetraammine) by mistake and summarize the intervention methods. Methods Patients with severe poisoning caused by poisoned rats were enrolled in this study from January 2010 to January 2015. The patients in the observation group received intensive hemoperfusion (n = 45) and the control group received conventional hemoperfusion (n = 45) Clinical data analysis. Results The control group of 45 patients, including 23 males and 22 females; mean age (4.75 ± 2.68) years; cured 36 cases, 9 died; convulsions stopped in children (3.96 ± 1.14) d; hospital stay (11.7 ± 3.5 d. There were 24 males and 21 females in the observation group. The average age was (4.58 ± 2.24) years old. All 45 cases were cured without any deaths. The twitch time was 1.83 ± 0.57 d and the hospitalization time was 7.8 ± 2.1 days. Conclusion Intensive blood perfusion through the femoral vein can significantly reduce the mortality rate of tetramine poisoning children, shorten the convulsions time, hospitalization time.