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目的了解宜昌地区女性患者宫颈人乳头瘤病毒(HPV)的感染状况。方法选择2011年7月2013年7月三峡大学第一临床医学院检验科进行宫颈分泌物HPV DNA检测的女性患者1 182例,对其HPV DNA检测结果进行回顾性分析。结果宜昌地区HPV平均感染率约32.83%(388/1 182),其中妇科门诊就诊患者中低危型HPV(6/11型)感染率约25.00%(73/292),而妇科患者高危型HPV感染率高达61.19%(298/487),且宫颈癌患者HPV高危型感染率达63.77%,显著高于其他宫颈相关疾病。结论宜昌地区高危型HPV感染率较高,而宫颈癌患者高危型HPV感染率更是超过60%。建议宜昌地区将高危型HPV DNA检测作为普通女性人群的常规体检项目,为早期发现宫颈病变及宫颈癌的防治提供实验室依据。
Objective To understand the infection status of cervical HPV in female patients in Yichang. Methods A total of 1 182 female patients with cervical secretions HPV DNA test from July 2011 to July 2013 from the First Clinical Medical College of the Three Gorges University were retrospectively analyzed. Results The average infection rate of HPV in Yichang was about 32.83% (388/1 182). The infection rate of low-risk type HPV (6/11 type) in gynecology clinic was about 25.00% (73/292) The infection rate was as high as 61.19% (298/487), and the rate of high-risk HPV infection in cervical cancer patients was 63.77%, significantly higher than other cervical-related diseases. Conclusion The prevalence of high-risk HPV in Yichang is high, while the prevalence of high-risk HPV in cervical cancer is more than 60%. It is suggested that high-risk HPV DNA testing in Yichang should be taken as a regular physical examination item for common female population, providing a laboratory basis for early detection of cervical lesions and prevention and treatment of cervical cancer.