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目的观察脉冲染料激光在婴儿体表血管瘤治疗中的效果。方法选取医院2016年10月-2017年3月收治的体表血管瘤患儿61例作为观察组,所有患儿均予以脉冲染料激光治疗,同时选择于我院确诊的60例未做任何治疗的体表血管瘤患儿作为对照组,术后随访6个月,在同一条件下采用同一相机进行摄片,评价治疗效果。随访期间,统计比较2组患者并发症发生情况。采用自制问卷调查观察2组患者的治疗满意度。结果观察组61例患儿中,2例接受1次治疗,10例接受2次治疗,29例接受过3次治疗,其余20例接受>3次治疗,总有效率达91.8%。对照组总有效率为16.7%,其余50例患者在随访第3个月瘤体可见明显增大。观察组总有效率明显高于对照组,差异有统计学意义(χ~2=12.584,P<0.05)。观察组患儿61例,并发症发生率13.1%(8/61),其中有4例(6.6%)患儿在治疗后3 d内瘤体表面出现大小水泡,采用烧伤膏涂抹1周后脱痂愈合;2例(3.3%)患儿激光治疗后瘤体顶部破溃,口服药物干预后好转但留下瘢痕;2例(3.3%)患儿由于瘤体增长十分迅速,单独采用激光治疗后仍明显增大,辅助药物进行干预后效果增强。对照组60例患儿中,7例(11.7%)患儿出现瘤体顶部自发破溃而遗留瘢痕,4例(6.7%)患儿发生感染,并发症发生率18.3%。2组并发症发生率对比差异无统计学意义(χ2=0.965,P>0.05)。观察组患者治疗满意度90.2%高于对照组的73.3%,差异有统计学意义(χ~2=7.194,P<0.05)。结论脉冲染料激光在婴儿体表血管瘤治疗中的效果突出,具有疗效显著、安全性高等优势,值得在临床实践中推广。
Objective To observe the effect of pulsed dye laser in the treatment of infantile hemangiomas. Methods Totally 61 children with body surface hemangiomas admitted from October 2016 to March 2017 in our hospital were selected as the observation group. All children were treated with pulsed dye laser and 60 cases without any treatment Body surface hemangioma children as a control group, after 6 months of follow-up, under the same conditions using the same camera for radiotherapy to evaluate the therapeutic effect. During the follow-up period, the comparisons were made between two groups of patients. The self-made questionnaire was used to observe the satisfaction of the two groups of patients. Results Among the 61 children in the observation group, 2 received 1 treatment, 10 received 2 treatments, 29 received 3 treatments, and the remaining 20 received> 3 treatments with a total effective rate of 91.8%. The control group, the total effective rate was 16.7%, the remaining 50 patients were observed at the 3rd month of the tumor was significantly increased. The total effective rate in the observation group was significantly higher than that in the control group, with significant difference (χ ~ 2 = 12.584, P <0.05). The observation group of 61 cases of children, the complication rate was 13.1% (8/61), of which 4 cases (6.6%) in the 3 days after treatment, the size of the blisters on the surface of the tumor, with the burn ointment after 1 week After the laser treatment, the top of the tumor was ruptured in 2 patients (3.3%), but scarring was observed after the oral medication was given. In 2 (3.3%) children, the tumors grew rapidly and were treated with laser alone Still significantly increased, the effect of supplementary drugs after intervention increased. Among 60 children in the control group, 7 cases (11.7%) developed spontaneous ulceration and scarring at the top of the tumor, and 4 cases (6.7%) developed infection with a complication rate of 18.3%. There was no significant difference in complication rates between the two groups (χ2 = 0.965, P> 0.05). The treatment satisfaction rate in the observation group was 90.2% higher than that in the control group (73.3%), the difference was statistically significant (χ ~ 2 = 7.194, P <0.05). Conclusion Pulsed dye laser in the treatment of infant hemangioma outstanding results, with significant efficacy, safety and other advantages, it is worth promoting in clinical practice.