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[目的]探讨影响腮腺癌治疗效果及预后的因素。[方法]回顾分析284例腮腺癌临床资料,分析性别、年龄、病理类型、临床分期及治疗方法等对5年、10年生存率的影响。[结果]全组病例5年、10年生存率分别为73.2%、52.0%。单因素分析显示病理类型(P=0.03)、临床分期(P=0.00)、面神经是否受累(P=0.00)是腮腺癌生存的预后因素,年龄(P=0.08)、性别(P=0.06)对腮腺癌预后无显著影响。原发灶首次单纯手术与手术加术后放疗相比较生存率差异无统计学意义(P>0.05),但两组与再次手术及再次手术+放疗组比较生存率差异具有统计学意义(P<0.05)。[结论]手术是治疗腮腺癌的主要手段,首次手术、临床分期、病理类型及面神经是否受累是影响腮腺癌治疗效果及预后的重要因素。
[Objective] To explore the factors that affect the therapeutic effect and prognosis of parotid cancer. [Methods] A retrospective analysis of 284 cases of parotid gland cancer clinical data, analysis of gender, age, pathological type, clinical stage and treatment of 5-year, 10-year survival rate. [Results] The 5-year and 10-year survival rates of all patients were 73.2% and 52.0% respectively. Univariate analysis showed that the pathological type (P = 0.03), clinical stage (P = 0.00), and facial nerve involvement (P = 0.00) were the prognostic factors for the survival of parotid gland carcinoma (P = 0.08) Parotid gland cancer prognosis had no significant effect. There was no significant difference in survival rate between primary surgery and operation and postoperative radiotherapy for the first time (P> 0.05), but there was significant difference between two groups in re-operation and re-operation plus radiotherapy (P < 0.05). [Conclusion] Surgery is the main means of treatment of parotid gland cancer. The first operation, clinical stage, pathological type and facial nerve involvement are the important factors that affect the therapeutic effect and prognosis of parotid gland cancer.