增生性玻璃体视网膜病变是一种严重的眼疾 ,常导致视力下降甚至失明。它是孔源性视网膜脱离手术失败、复发以及眼外伤致盲的主要原因之一。其发病机制目前尚未完全明了。大多学者认为细胞因子与PVR的发生发展有密切关系。从免疫学发病机制的角度 ,对与PVR有关的细胞因子及其可能作用机制加以综述 ,从而为PVR的诊断和治疗提供新的思路和切入点。 Proliferative vitreoretinopathy is a serious eye disease, often leading to decreased vision or even blindness. It is one of the main reasons for the failure, recurrence and blindness of eye-derived retinal detachment. The pathogenesis is not yet fully understood. Most scholars believe that cytokines and PVR are closely related to the occurrence and development. From the perspective of the pathogenesis of immunology, we reviewed the PVR-related cytokines and their potential mechanisms of action, and provided new ideas and breakthroughs for the diagnosis and treatment of PVR.