中耳胆脂瘤临床与病理特征已相当清楚,但其分类和发病机理还存在较多争议。为探讨其发病机理,选用50只成年健康无中耳感染的粟鼠进行实验研究。方法是在全麻下翻起皮肤骨膜,钻开听泡,让皮肤骨膜复位愈合约一周后,用2个注射针经皮刺入听泡钻孔内,经一个针将0.2ml未稀释的丙二醇 The clinical and pathological features of middle ear cholesteatoma are quite clear, but there are still many controversies about its classification and pathogenesis. In order to explore its pathogenesis, we selected 50 adult healthy middle ear infected mice to do experimental research. The method is to turn the skin periosteum under general anesthesia, drilling to listen to the bubble, the skin periosteum reduction healing about a week after the piercing with 2 injection needle perforation drilling bubble through a needle will be 0.2ml undiluted propylene glycol