目的 :无机砷 (i As)已知是作为氧化应激的诱发金属。作为其原因 :1 ) i As在生物体内和作为抗氧化物作用的谷胱甘肽(GSH)以非酶结合。2 ) i As(特别是 5价砷 )在生物体内认为在甲基化时消耗 GSH。因此 ,本次在慢性的水土性砷中毒地区进行了病例—对照研究 ,探讨由 i As所引起 Purpose: It is known that inorganic arsenic (iAs) is an inducer of oxidative stress. The reason for this is as follows: 1) i As is non-enzymatically bound to glutathione (GSH) acting as an antioxidant in the living body. 2) i As (especially pentavalent arsenic) is thought to consume GSH when methylated in the living body. Therefore, this case-control study was conducted in areas of chronic aquatic arseniasis to investigate the effects of i As