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Summary: In order to investigate the influence of radiation therapy after the treatment of maxillaryimplant-supported prostheses, 27 patients received a total of 131 implants in maxilla after oral cancertreatment and/or reconstructive surgery. Among them, 25 received maxillary implant-supportedprostheses. The cumulative survival rates of implants and prostheses were evaluated by the product-limit-estimates method according to Kaplan-Meier. The cumulative survival rate of implants andprostheses in irradiated patients was compared with that in non-irradiated patients by statistical Log-rank test. The results showed that 112 implants were observed after implant loading. The implantscumulative survival rate was approximately 65 % for overall patients. The cumulative prosthesis suc-cessful rate was approximately 88 % for all 25 patients. Log-rank test analysis revealed that therewas a significant difference in cumulative implants survival rates between non-irradiated and irradiat-ed maxillary bone (P＜0. 01). It was concluded that the implants and prostheses in irradiated pa-tients have significantly lower survival rates than in non-irradiated patients.