大疱性表皮松解萎缩坏死型药疹是药疹中最严重的一型,少见而凶险,病情危重,死亡率高,应引起临床各科医师的高度重视。我科近10年来急诊收住院抢救此类药疹患者14例,特分析报道如下。1 临床资料1.1 一般资料14例中,男性4例,女性10例,年龄最小7岁,最大66岁,平均33±17.13岁,其中7～10岁3例。职业:农民10例,学生3例,工人1例。发病前患感冒5例,牙痛,腹泻,足扭伤,胆囊炎,慢性支气管炎,癫痫,颈椎病头晕各1例,不明原因发热伴躯干部出现红斑、痱子样皮疹2例。致敏药物:解热镇痛药 Epidermolysis bullosa atrophy necrosis drug eruption is one of the most serious type of drug eruption, rare and dangerous, critically ill, high mortality rate, should attract the attention of all clinical physicians. In recent 10 years, our department received emergency treatment in hospital for such cases of drug-eradication in 14 cases, the special report as follows. 1 Clinical data 1.1 General Information 14 cases, 4 males and 10 females, the youngest 7 years old, maximum 66 years old, with an average of 33 ± 17.13 years of age, of which 7 to 10 years old in 3 cases. Occupation: 10 farmers, 3 students, 1 worker. Pre-onset influenza in 5 cases, toothache, diarrhea, sprained foot, cholecystitis, chronic bronchitis, epilepsy, cervical spondylosis 1 case of dizziness, unexplained fever with the emergence of erythema torso, prickly heat rash in 2 cases. Sensitization drugs: antipyretic analgesics