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支气管扩张(支扩)表现为痰多、病情反复加重和气道进行性破坏,患者深受其苦。目前已知红霉素治疗另一种气道化脓性病变—弥漫性泛细支气管炎是有效的,故作者研究小剂量红霉素治疗特发性支扩的疗效。 方法和对象 采用随机双盲安慰剂对照试验法。受试对象均为经高分辨CT证实的稳定期支扩患者。人选标准:24小时痰量,第一秒用力呼气容积(FEV_1)及用力肺活量(VC)的波动均小于10％,无咳嗽、呼吸困难、气喘、发热或胸
Bronchiectasis (bronchiectasis) manifested as phlegm, the disease repeatedly increased and airway destruction, patients suffer. Erythromycin is currently known to treat another airway purulent lesion - diffuse panbronchiolitis is effective, so the author of a small dose of erythromycin in the treatment of idiopathic dilated curative effect. Methods and Subjects A randomized double-blind placebo-controlled trial was used. Subjects were high-resolution CT confirmed stable patients with branch expansion. Criteria for selection: Sputum volume in 24 hours, forced expiratory volume in the first second (FEV_1), and forced vital capacity (VC) fluctuations were less than 10% with no cough, dyspnea, wheezing, fever or chest