作者观察到结核病人应用胺硫脲和异烟肼联合治疗时,有8％发生过敏反应,其中5％发生红斑色素沉着皮疹。由此作者用二药联合治疗60例白癜风。所有的患者做了结核菌素试验、胸透、查痰、血沉检查以排除肺结核病及肺外结核。由于胺硫脲自肝代谢,治疗前还作了肝功(SGPT)检查。这些患者的白斑病期、范围、大小不一。为随访观察药物效果而进行了连续的照相记录。两例患者取色素减退斑,色素恢复斑及正常皮肤作活检。治疗经过:成人异烟肼剂量300毫克/日、胺硫脲150毫克每天睡前一剂服用。儿童剂量减半。服药 The authors observed an allergic reaction in 8% of tuberculosis patients treated with combination of amine thiourea and isoniazid, and 5% developed erythema pigmented rash. The authors used two drugs combined treatment of 60 cases of vitiligo. All patients did tuberculin test, chest X-ray, sputum aspiration, ESR to rule out tuberculosis and extra-pulmonary tuberculosis. Since the thiamine thiamine metabolism from the liver before treatment also made a liver function test (SGPT). White spot of these patients, the scope, size. Follow-up observation of drug effects and continuous photographic records. Two patients with hypopigmented spots, pigmented spots and normal skin for biopsy. After treatment: adult isoniazid dose of 300 mg / day, thiamine 150 mg a day before bedtime taking. Child dose halved. Take medicine