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目的研究激光虹膜根切术对原发性急性闭角型青光眼(APACG)缓解期患者眼压及中央前房深度的影响,为临床治疗提供参考。方法随机选取2013年5月至2016年6月惠州市第一人民医院门诊治疗的APACG缓解期患者100例,依随机表对照法分为治疗组50例和对照组50例。两组患者均接受视力检查,停用降压药物5 d后测量眼压及房水流畅系数,治疗组接受激光虹膜根切术治疗,对照组接受激光周边虹膜成形术治疗。治疗前后3 d进行超声生物显微镜(UBM)检查,并且于治疗后2 h、6 h及3 d时测量眼压。结果治疗后治疗组患者视力恢复优于对照组,差异有统计学意义(P<0.05);治疗3 d后治疗组眼压优于对照组,差异有统计学意义(P<0.05);治疗组中央前房深度比对照组深,差异有统计学意义(P<0.05)。结论 APACG患者经激光虹膜根切术较经激光周边虹膜成形术后眼压稳定,视力更好,中央前房深度更深,并且激光虹膜根切术能有效解除瞳孔阻滞。
Objective To study the effect of laser iridectomy on intraocular pressure (IOP) and central anterior chamber depth in patients with primary acute angle closure glaucoma (APACG) remission and to provide reference for clinical treatment. Methods A total of 100 APACG-remission patients were selected randomly from May 2013 to June 2016 in Huizhou First People’s Hospital. According to randomized controlled trials, 50 patients were divided into treatment group and control group. The patients in both groups underwent visual acuity test. The intraocular pressure and aqueous fluid flow coefficient were measured after antihypertensive drugs were stopped for 5 days. The treatment group received laser iridectomy and the control group received laser peripheral iris angioplasty. Ultrasound biomicroscopy (UBM) was performed 3 days before and after treatment, and intraocular pressure was measured at 2 h, 6 h and 3 d after treatment. Results After treatment, the visual acuity recovery of the treatment group was better than that of the control group (P <0.05), and the IOP of the treatment group was better than that of the control group after 3 days of treatment (P <0.05) The central anterior chamber depth than the control group, the difference was statistically significant (P <0.05). Conclusion APACG laser iridectomy laser IOP after laser peripheral ileum stabilization, better visual acuity, central anterior chamber deeper, and laser iridectomy can effectively lift the pupil block.