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目的探讨轮状病毒肠炎患儿心肌酶谱和肌钙蛋白改变及临床意义。方法对72例确诊为轮状病毒肠炎患儿的心肌酶谱(AST、LDH、HBDH、CK、CK-MB)、肌钙蛋白和心电图进行检查,并按脱水程度进行分类比较,所获数据经方差分析、χ2检验。结果32例(44.45%)轮状病毒肠炎患儿心肌酶升高,19例(26.39%)肌钙蛋白升高,心电图异常35例(48.6%),较正常对照组差异有统计学意义(P<0.01)。无脱水和轻度脱水患儿心肌酶升高12例(30.77%),肌钙蛋白升高3例(7.69%);中度和重度脱水患儿分别是20例(60.61%)和16例(48.49%),二者比较差异有统计学意义(P<0.01)。结论轮状病毒肠炎易致心肌损害,出现心肌酶肌钙蛋白和心电图改变,预后良好。
Objective To investigate the changes of myocardial enzymes and troponin in children with rotavirus enteritis and its clinical significance. Methods The myocardial enzymes (AST, LDH, HBDH, CK, CK-MB), troponin and electrocardiogram in 72 children diagnosed as rotavirus enteritis were examined and compared according to the degree of dehydration. The data obtained were Analysis of variance, χ2 test. Results Thirty-two patients (44.45%) had elevated myocardial enzymes, 19 (26.39%) had elevated troponin and 35 (48.6%) had abnormal electrocardiogram compared with the normal control group (P <0.01). Myocardial enzymes were elevated in 12 (30.77%) and troponin (3) hyperplasia (7.69%) in children without dehydration and mild dehydration, 20 (60.61%) and 16 48.49%), the difference was statistically significant (P <0.01). Conclusions Rotavirus enteritis is easy to cause myocardial damage, myocardial enzymes troponin and ECG changes, the prognosis is good.