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目的探讨人乳头瘤病毒(HPVDNA)与电子阴道镜联合检测在子宫颈病变筛查中的诊断价值。方法随机抽取1033例患者进行人乳头瘤病毒(HPVDNA)检测,与病理结果进行比较。结果 HPV检查阳性56例,占5.42%,其中33例低危型(3.19%)、23例高危型(2.22%)。对HPV呈阳性的56例进行阴道镜检查及镜下活组织病理检查,发现异常阴道镜图像44例。与病理组织学对照,低危型HPV(慢性宫颈炎18例、CINI8例、CINII5例、CINIII2例);高危型HPV(CINI10例、CINII7例、CINIII3例、SCC3例)。结论采用人乳头瘤病毒(HPV)检测技术辅助阴道镜检查,可以有效提高宫颈癌前病变和癌变的检出率,对于及时发现癌前病变,防治宫颈癌具有显著意义。
Objective To investigate the diagnostic value of HPV DNA and electronic colposcopy in the screening of cervical lesions. Methods A total of 1033 patients were selected for HPV DNA test and compared with pathological results. Results The positive results of HPV test were 56 cases (5.42%), of which 33 were low-risk (3.19%) and 23 were high-risk (2.22%). Fifty-six HPV positive cases were examined by colposcopy and biopsy under the microscope, and 44 cases were found abnormal colposcopy images. Compared with the histopathology, low-risk HPV (chronic cervicitis in 18 cases, CINI in 8 cases, CINII in 5 cases, CINIII in 2 cases), high-risk HPV (CINI in 10 cases, CINII in 7 cases, CINIII in 3 cases and SCC in 3 cases). Conclusions The use of human papillomavirus (HPV) detection technology to assist colposcopy can effectively improve the detection rate of cervical precancerous lesions and canceration, which is of great significance for timely detection of precancerous lesions and prevention and treatment of cervical cancer.