β-血小板球蛋白(β-TG)是血小板特异的蛋白质,有抑制血管内皮细胞合成前列环素的作用。当血小板被激活时它被释放至血浆中。Cella报告在血管栓塞性疾病中,血浆β-TG浓度增高,提示体内血小板功能亢进。本文测定了血栓性疾病、肾炎及正常人共26例乏血小板血浆的β-TG,并同时测定循环性血小板聚集物、血小板聚集试验和血浆抗凝血酶Ⅲ(AT Ⅲ)活力。 材料和方法;β-TG测定用放射免疫法,试剂为Amersham厂产品。抽血2.5 ml注入药箱提供的 β-thromboglobulin (β-TG) is a platelet-specific protein that inhibits the synthesis of prostacyclin by vascular endothelial cells. When platelets are activated, they are released into the plasma. Cella reports elevated plasma β-TG levels in vascular embolism, suggesting in vivo platelet function. In this study, β-TG in 26 patients with thrombotic disease, nephritis and normal controls were assayed for platelet aggregation, platelet aggregation and plasma levels of antithrombin Ⅲ (AT Ⅲ). Materials and methods; β-TG determination by radioimmunoassay, reagents for the Amersham plant products. Blood 2.5 ml injection kit provided