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目的:探讨老年原发性高血压患者夜间血压与蛋白尿的关系。方法:老年高血压患者随机分为两组,晨起或睡前口服氯沙坦50 mg,12周前后复查对比动态血压及尿白蛋白定量。结果:睡前服药组夜间收缩压及尿蛋白定量显著降低。结论:老年高血压患者睡前服用氯沙坦可有效控制夜间血压,显著降低尿蛋白。
Objective: To investigate the relationship between nocturnal blood pressure and proteinuria in elderly patients with essential hypertension. Methods: Elderly hypertensive patients were randomly divided into two groups, losartan 50 mg orally at bedtime or before going to bed, check the dynamic blood pressure and urinary albumin quantitation before and after 12 weeks. Results: At night, the systolic blood pressure and the proteinuria of urinary protein in the medication group were significantly lower at bedtime. Conclusion: Losartan before bedtime in elderly hypertensive patients can effectively control nocturnal blood pressure and significantly reduce urinary protein.