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目的评价复方丹参注射液联合山莨菪碱治疗小儿急性肾小球肾炎的临床疗效。方法将小儿急性肾小球肾炎患者120例,随机分为对照组和观察组,各60例。两组均给予常规治疗,观察组在此基础上予复方丹参注射液联合山莨菪碱治疗,2周后观察疗效。结果两组患儿水肿、高血压、血尿、蛋白尿的变化及血清超氧化物歧化酶(SOD)活性比较差异均具有统计学意义(P<0.05)。结论应用复方丹参注射液联合山莨菪碱治疗小儿急性肾小球肾炎的疗效显著,优于常规治疗组。
Objective To evaluate the clinical efficacy of compound Danshen injection combined with anisodamine in the treatment of pediatric acute glomerulonephritis. Methods A total of 120 children with acute glomerulonephritis were randomly divided into control group and observation group, with 60 cases each. The two groups were given conventional treatment, the observation group on the basis of compound Danshen injection combined with anisodamine treatment, 2 weeks after the treatment effect. Results The edema, hypertension, hematuria, proteinuria and serum superoxide dismutase (SOD) activity in both groups were significantly different (P <0.05). Conclusion The application of compound Danshen injection combined with anisodamine treatment of children with acute glomerulonephritis significant effect, better than the conventional treatment group.