报告23例流行性出血热患者皮肤免疫荧光检查结果。发热期4例,少尿期5例,多尿期9例,恢复期5例。所有的真皮血管壁和表皮基底膜带有IgM 沉积,其中6例真皮毛细血管壁有C_3沉积,5例有IgA 沉积,未发现有IgG 沉积在血管壁。皮损与外观正常皮肤的改变无明显差别。认为免疫复合物在血管壁的形成及沉积在本病的发病机理上起一定作用。表皮基底膜带IgM 沉积可能主要与患者血浆中存在IgM 自身抗体有关。 Report 23 cases of epidemic hemorrhagic fever skin immunofluorescence test results. 4 cases of fever, oliguria in 5 cases, polyuria in 9 cases, recovery in 5 cases. All dermal vascular wall and epidermal basement membrane with IgM deposition, of which 6 cases of dermal capillary wall deposition of C_3, IgA deposition in 5 cases, no deposition of IgG in the vessel wall. There is no significant difference between the lesions and normal skin changes. It is believed that the formation and deposition of immune complexes in the vascular wall play a role in the pathogenesis of this disease. Epithelial basement membrane IgM deposition may be mainly associated with the presence of IgM autoantibodies in the patient’s plasma.