甲基精氨酸包括单甲基精氨酸和二甲基精氨酸 ,后者包括非对称性与对称性二甲基精氨酸。其中 ,单甲基精氨酸和非对称性二甲基精氨酸是内源性NOS抑制剂 ,它们和血管内皮功能失调密切相关 ,因而成为人们研究的热点。本文将对其代谢、生化与药理作一综述 Methyl arginine includes monomethylarginine and dimethylarginine, the latter including asymmetric and symmetrical dimethylarginine. Among them, monomethyl arginine and asymmetric dimethyl arginine are endogenous NOS inhibitors, which are closely related to vascular endothelial dysfunction, which has become a hot research area. This article will review its metabolism, biochemistry and pharmacology