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目的:儿童期探讨血脂紊乱儿童颈动脉弹性血脂各项指标与颈总动脉Ep和β的相关性。方法:选择2014年1月至2015年12月珠海市妇幼保健院对30例血脂紊乱组儿童和30例正常对照儿童进行血脂各项指标测定,应用ET技术检测双侧颈动脉弹性,并对血脂各项指标与Ep、β进行相关性分析。结果:血脂紊乱组的Ep、β较对照组增高,血管Ep与总胆固醇、三酰甘油和低密度脂蛋白的相关系数分别为0.478,0.523和0.541;β与总胆固醇、三酰甘油和低密度脂蛋白的相关系数分别为0.346,0.534和0.643。结论:总胆固醇、低密度脂蛋白是血管Ep增高,β增加的主要危险因素,提示在儿童期控制血脂水平亦是预防发生早期动脉弹性下降的关键。
Objective: To explore the correlation between the indexes of carotid artery elastic lipids and the common carotid artery Ep and β in children with dyslipidemia during childhood. Methods: From January 2014 to December 2015, Zhuhai Municipal Maternal and Child Health Hospital of Zhuhai City, 30 cases of dyslipidemic children and 30 normal children were measured for the determination of lipid, the application of ET technology to detect bilateral carotid artery elasticity, and lipid The indicators and Ep, β correlation analysis. Results: The Ep and β in the dyslipidemia group were higher than those in the control group. The correlation coefficients of Ep with total cholesterol, triglyceride and low density lipoprotein were 0.478, 0.523 and 0.541, respectively. Β and total cholesterol, triglyceride and low density The correlation coefficients of lipoproteins were 0.346, 0.534 and 0.643, respectively. Conclusion: Total cholesterol and low density lipoprotein are the main risk factors for the increase of blood vessel Ep and β, suggesting that controlling blood lipid levels in childhood is also the key to prevent the decline of early arterial elasticity.