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本文介绍的方案是一种序贯冲击疗法。对晚期卵巢癌能改善其生存率是值得重视的一个苗头。但作者介绍的冲击剂量太大,因此必然副作用也大,作者就有1例因副作用而死亡。据大多数资料介绍,冲击疗法剂量一般为常用剂量之4—5倍。如用环磷酰胺冲击疗法一般一次用0.8—1.0克。因为周期非特异性药物如环磷酰胺,氮芥等在剂量加倍时,对瘤细胞的杀伤能力可增加数倍甚至可达100倍。所以冲击剂量不一定要那么大,否则超出了机体安全耐受范围,望读者注意。
This article describes the program is a sequential impact therapy. On advanced ovarian cancer can improve its survival rate is worth attention to a sign. However, the author introduced the impact dose is too large, so inevitable side effects are also large, the author had 1 case died of side effects. According to most of the information, the impact therapy dose is usually 4-5 times the usual dose. As with cyclophosphamide therapy generally use 0.8-1.0 grams. Because the cycle of non-specific drugs such as cyclophosphamide, nitrogen mustard, etc. doubling the dose, the tumor cell killing ability can increase several times or even up to 100 times. So the impact dose is not necessarily so big, or beyond the scope of the body’s safety tolerance, hope the reader’s attention.