IgA肾病与过敏性紫癜性肾炎临床病理比较

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比较了28例IgA肾病(IgAN)和19例过敏性紫癜性肾炎(HSPN)的临床和病理资料,结果表明:I-gAN与HSPN有许多相似之处,二者血尿发生率、男女发病率和高血压发生率相似;肾脏病理Ⅱ、Ⅲ、Ⅴ和Ⅵ级发生率相似;免疫病理IgAG型和IgAM型的发生率亦相似。但二者之间亦有不同之处,IgAN发病年龄、肉眼血尿发生率、血清IgA升高率高于HSPN;肾病综合征(NS)发生率低于HSPN;且IgANⅣ级病变和免疫荧光IgAGM型的发生率高于HSPN。上述差别均有统计学意义。此外,IgAN肾功能异常发生率高于HSPN,单纯IgA沉积型低于HSPN,但无统计学意义。这些资料为进一步认识二者的关系提供了临床依据 The clinical and pathological data of 28 cases of IgA nephropathy (IgAN) and 19 cases of Henoch-Schonlein purpura nephritis (HSPN) were compared. The results showed that there were many similarities between I-gAN and HSPN, the incidence of hematuria and the incidence of male and female The incidence of hypertension was similar; the incidence of renal pathology Ⅱ, Ⅲ, Ⅴ and Ⅵ was similar; the incidence of immunopathological IgAG and IgAM were similar. However, there are also differences between the two groups. The incidence of IgAN, the incidence of gross hematuria and serum IgA were higher than those of HSPN. The incidence of nephrotic syndrome (NS) was lower than that of HSPN. IgANⅣ-class lesions and immunofluorescence IgAGM The incidence of HSPN is higher than that of HSPN. The above differences were statistically significant. In addition, the incidence of IgAN renal dysfunction than HSPN, IgA deposition was lower than HSPN, but not statistically significant. These data provide a clinical basis for further understanding of the relationship between the two
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