硫酸庆大霉素滴眼液和硫酸妥布霉素滴眼液的稳定性研究

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市售的硫酸庆大霉素滴眼液和硫酸妥布霉素滴眼液浓度通常为3mg/ml,为了提高各种眼外伤及严重感染的治疗效果,作者配制了硫酸庆大霉素滴眼液和硫酸妥布霉素滴眼液,并研究两种滴眼液于冷藏条件(4~8℃)下的稳定性。通过混合市售的硫酸庆大霉素滴眼液(3mg/ml)和硫酸庆大霉素注射液(40 mg/ml),制成浓度为13.6 mg/ml的硫酸庆大霉素滴眼液。硫酸妥布霉素滴眼液也同样配制。将滴眼液分装于塑料瓶中,于4~8℃下存放,并定期取样,用荧光偏振免疫分析法和 Commercially available gentamicin sulfate eye drops and tobramycin sulfate eye drops concentration is usually 3mg / ml, in order to improve a variety of ocular trauma and severe infection of the treatment effect, the preparation of gentamicin sulfate eye drops Solution and tobramycin sulfate eye drops, and studied the stability of the two eye drops under refrigerated conditions (4 to 8 ° C). Gentamicin sulfate eye drops (13 mg / ml) were prepared by mixing commercially available gentamicin sulfate eye drops (3 mg / ml) and gentamicin sulfate injection (40 mg / ml) . Tobramycin sulfate eye drops are also formulated. The eye drops were dispensed in plastic bottles, stored at 4 ~ 8 ℃, and regular sampling, fluorescence polarization immunoassay and
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