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Two-way feedback of human body was published in 1992. The sensation of two-way feedback of body is a spe-cial system of human reaction, which maintains and regulates symmetry and balance of human body. The human two-way feedback reacts to human health. For human overall health and delay decrepitude, it is necessary to pay attention to the stimulations (passive acceptance and initiative interventions) and relevant influences in human body and the stimu-lative effect. In this paper, the experimental research of stimulation and an example of two-way feedback in human body are given. And lay a foundation of prevention, medical treatment and hygiene of human overall health.