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结缔组织生长因子(connective tissue growth factor,CTGF)是一种新发现的细胞因子,是细胞外间质及纤维化领域新的研究热点。本文重点讨论CTGF的结构、功能以及在肝纤维化形成中的作用,从而为有效防治肝纤维化提供理论依据。
Connective tissue growth factor (CTGF) is a newly discovered cytokine, which is a new research hotspot in extracellular matrix and fibrosis. This article focuses on the structure, function and role of CTGF in the formation of hepatic fibrosis to provide a theoretical basis for the effective prevention and treatment of hepatic fibrosis.