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目的:分析碘盐浓度标准调整前后厦门市8 ~ 10岁儿童和孕妇碘营养状况，评价新标准碘盐调整政策对厦门市的适宜性。方法:在调整前（2011年）和调整后（2018年），采用横断面调查方法和分层整群抽样法，选择厦门市所有下辖的6个区为调查点。抽样检测居民户和孕妇家中盐碘，8 ~ 10岁儿童和孕妇尿碘，8 ~ 10岁儿童甲状腺肿大情况，并对检测结果进行比较分析。结果:调整后儿童盐碘中位数为23.5 mg/kg，低于调整前的28.9 mg/kg，调整后孕妇盐碘中位数为23.7 mg/kg，低于调整前的29.2 mg/kg，差异均有统计学意义（n Z = - 10.512、- 12.622，n P均< 0.05）；合格碘盐食用率由调整前97.1%（1 608/1 656）下降为调整后95.7%（1 196/1 250），差异有统计学意义（χn 2 = 4.250，n P 0.05）。8 ~ 10岁儿童尿碘中位数由调整前（625份尿样）的204.2 μg/L下降为调整后（1 250份尿样）的183.9 μg/L，差异有统计学意义（ n Z = - 3.583，n P 0.05）。调整前、后8 ~ 10岁儿童甲状腺肿大率分别为1.1%（14/1 239）和0.2%（2/1 253），差异有统计学意义（χ n 2 = 9.195，n P < 0.05）。n 结论:厦门市碘盐防控碘缺乏病措施总体落实到位，碘盐浓度标准调整后8 ~ 10岁儿童碘营养处于适宜水平，但孕妇存在碘缺乏风险。“,”Objective:To investigate the iodine nutritional status among children aged from 8 - 10 and pregnant women in Xiamen City before and after adjustment of salt iodine concentration, and scientifically evaluate the suitability of the new standard iodized salt adjustment policy for Xiamen City.Methods:In the pre-adjustment period (2011) and the post-adjustment period (2018), cross-sectional research methods and stratified cluster sampling methods were adopted in six districts of Xiamen City. The salt samples of residents and pregnant women, urine samples of children aged from 8 - 10 and pregnant women were collected to determine the iodine level; thyroid of children aged from 8 - 10 was examined. Changes in salt iodine, urine iodine and goiter prevalence before and after adjusting iodine content of salt were compared.Results:The median of salt iodine in residents after the adjustment (23.5 mg/kg) was significantly lower than that of before (28.9 mg/kg, n Z = - 10.512, n P < 0.05), the median of salt iodine in pregnant women after the adjustment (23.7 mg/kg) was significantly lower than that of before (29.2 mg/kg, n Z = - 12.622, n P < 0.05); the consumption rate of qualified iodized salt in residents after the adjustment (95.7%, 1 196/1 250) was significantly lower than that of before (97.1%, 1 608/1 656; χ n 2 = 4.250, n P 0.05). There was significant difference in median urinary iodine (from 204.2 to 183.9 μg/L, detected in 652, 1 250 urine samples, respectively) of children aged 8 - 10 years ( n Z = - 3.583, n P 0.05). The thyroid goiter rate of children aged 8 - 10 years had reduced from 1.1% (14/1 239) to 0.2% (2/1 253), the difference was statistically significant (χ n 2 = 9.195, n P < 0.05).n Conclusions:As a whole, the measure of control and prevention of iodine deficiency disorders through iodized salt is implemented well in Xiamen City. After adjustment of salt iodine concentration, the iodine status of children aged from 8 to 10 is adequate, but the pregnant women has showed iodine deficiency.