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目的:应用超声组织速度显像(TVI)技术对持续性房颤患者左心耳充盈和排空功能变化特点进行研究。方法:选择29例持续性房颤患者(房颤组)和31例对照者(对照组),在食管超声心动图(TEE)条件下获取左心耳超声图像,应用TVI技术对左心耳壁各节段收缩期峰值速度(PSV)和舒张早期峰值速度(PDVE)及其相关指标进行定量分析。结果:对照组左心耳壁顶部PSV和PDVE高于其余节段(P<0.05),房颤组左心耳壁各节段PSV和PDVE较对照组均降低(P<0.01)。对照组心耳顶部PSV与左心耳面积变化率(LAA-EF)和左心耳充盈速度(LAA-EV)呈正相关(r=0.656、0.712,P<0.001),房颤组心耳顶部PSV与左房腔内径(LADd)呈线性负相关(r=-0.66,P<0.001)。结论:TVI技术可定量评价左心耳排空及充盈功能,左心耳顶部PSV是反映左心耳整体排空功能的有效指标。
Objective: To study the characteristics of filling and evacuation of left atrial appendage in patients with persistent atrial fibrillation by using ultrasonic tissue velocity imaging (TVI). Methods: Twenty-nine patients with persistent AF (AF) and 31 healthy controls (control group) were enrolled in this study. Left atrial appendage was obtained under esophageal echocardiography (TEE) The systolic peak velocity (PSV) and early diastolic peak velocity (PDVE) and related parameters were quantitatively analyzed. Results: The PSV and PDVE at the top of the left atrial appendage in the control group were higher than those in the other segments (P <0.05). PSV and PDVE in each segment of the left atrial appendage were lower in the AF group than those in the control group (P <0.01). In the control group, PSV was positively correlated with LAA-EF and LAA-EV (r = 0.656, 0.712, P <0.001) The inner diameter (LADd) showed a linear negative correlation (r = -0.66, P <0.001). Conclusion: The TVI technique can quantitatively evaluate the left atrial appendage emptying and filling function. The top PSV of the left atrial appendage is an effective index to reflect the whole emptying function of the left atrial appendage.