Novel Mechanism Idientii ed for Establishment of Kaposi's SarcomaAssociated Herpesvirus Latency

来源 :Bulletin of the Chinese Academy of Sciences | 被引量 : 0次 | 上传用户:wangyingygp
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On April 17,Journal of Virology published an article online entitled“Kaposi’s Sarcoma-Associated Herpesvirus-Encoded LANA Interacts with Host KAP1 to Facilitate Establishment of Viral Latency”by Prof.LAN Ke’s lab at the Institut Pasteur of Shanghai,Chinese Academy of Sciences.This article was also selected as a spotlight article of signifi cant interest by the editors.Kaposi’s sarcoma-associated herpesvirus(KSHV)typically displays two different phases in its life cycle,including the default latent phase as well as the lytic phase.This virus could establish a latent infection in a very short time(typically 24~48 hours)since its invasion into the host cell and stay there for the lifetime of the latter.The latent infection is the precondition of its pathogenesis and On April 17, Journal of Virology published an article online entitled “Kaposi’s Sarcoma-Associated Herpesvirus-Encoded LANA Interacts with Host KAP1 to Facilitate Establishment of Viral Latency ” by Prof. LAN Ke’s lab at the Institut Pasteur of Shanghai, Chinese Academy of Sciences Sciences.This article was also selected as a spotlight article of signifi cant interest by the editors. Kaposi’s sarcoma-associated herpesvirus (KSHV) typically displays two different phases in its life cycle, including the default latent phase as well as the lytic phase. virus could establish a latent infection in a very short time (typically 24 ~ 48 hours) since its invasion into the host cell and stay there for the lifetime of the latter. latent infection is the precondition of its pathogenesis and
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