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[期刊论文] 作者:Ai-lin LIU,Wen-wen LIAN,Xiao-c,
来源:中国药理学与毒理学杂志 年份:2017
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Effect of large cold deformation after solution treatment on precipitation characteristic and deform
[期刊论文] 作者:NING Ai-lin,LIU Zhi-yi,ZENG Su-min,
来源:中国有色金属学会会刊(英文版) 年份:2006
The effects of large cold deformation after solution treatment on the precipitation characteristic and deformation strength of 2024 and 7A04 Al alloys were inve...
[会议论文] 作者:Chao LI,Ai-lin LIU,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
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Rational drug screening on neuraminidase (NA) inhibitors of influenza virus using support vector mac
[会议论文] 作者:Ai-lin LIU,Chao LI,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
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Rational drug screening on neuraminidase (NA) inhibitors of influenza virus using support vector mac
[会议论文] 作者:Ai-lin LIU,Chao LI,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
Aim: Neuraminidase (NA) is one of the most important drug targets for antiinfluenza drugs, NA inhibitors are currently the main clinical medicines for the treatment of influenza virus infection, and m...
[期刊论文] 作者:WEI Ai-lin,LIU Shi-qing,TAO Hai-ying,PENG Hao,
来源:中华创伤杂志英文版 年份:2008
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Redistribution and re-precipitation of solute atom during retrogression and reaging of Al-Zn-Mg-Cu a
[期刊论文] 作者:NING Ai-lin,LIU Zhi-yi,PENG Bei-shan,ZENG Su-min,
来源:中国有色金属学会会刊(英文版) 年份:2007
The redistribution and re-precipitation of solute atom during retrogression and reaging of three different Al-Zn-Mg-Cu aluminum alloys were investigated. The re...
[会议论文] 作者:Ai-lin LIU,Mian ZU,Jian-song FANG,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
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Effects of DL0410 on the learning and memory deficit in APP/PS1 transgenic Alzheimer′s disease model
[期刊论文] 作者:Rong YAN,Ran-yao YANG,Ai-lin LIU,Guan-hua DU,,
来源:中国药理学与毒理学杂志 年份:2015
OBJECTIVE DL0410,one novel compound discovered inhigh throughput screening(HTS),was found to be a potent inhibitor for AChE and BuChE.Memory deficit mice model...
[会议论文] 作者:Mian ZU,Wei-Ling ZHOU,Ai-Lin LIU,Guan-Hua DU,
来源:第二届世界天然药物和传统药物药理学学术会议 年份:2012
AIM Influenza A virus (IAV) resistance to available antiviral agents urges us to discover new drugs.Natural flavonoids have been reported for their antiviral activities.In this paper, the anti-influen...
[会议论文] 作者:Ran-yao YANG,Jian-song FANG,Ai-lin LIU,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
Aim: Cdk5 is an a typical cyclin-dependent kinase localized in the brain, and its activity is dependent upon binding to p35.Cdk5/p35 plays an important role in the hyperphosphorylation of tau protein,...
[会议论文] 作者:Mian ZU,Wei-Ling ZHOU,Ai-Lin LIU,Guan-Hua DU,
来源:第二届世界天然药物和传统药物药理学学术会议 年份:2012
AIM The shortage of anti-viral drugs urge us to look for new lead compounds for developing new anti-influenza viral drug.In drug screening of influenza viral neuramindase (NA) inhibitors, theaflavin (...
Predictions of BuchE inhibitors using support vector machine (SVM) and naive Bayesian classification
[会议论文] 作者:Jian-song FANG,Ran-yao YANG,Ai-lin LIU,Guan-hua DU,
来源:The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份:2013
Aim: Butyrylcholinesterases (BuChE, EC 3.1.1.8) is emerging as an important pharmacological target in Alzheimers disease (AD) therapy.Due to high cost and laboriousness in experimental tests, it is ne...
[会议论文] 作者:Qiang Zeng,Wen-Cheng Cao,Yi-Xin Wang,Ai-Lin Liu,Wen-Qing Lu,
来源:第六届亚洲特大城市环境与公共健康论坛暨中国环境科学学会环境医学与健康分会2015年会 年份:2015
Disinfection by-products (DBPs) are ubiquitous environment chemicals that present in drinking water.To date, more than 600 kinds of DBPs with different physicoc...
[期刊论文] 作者:Ai-lin LIU,Wen-wen LIAN,Xiao-cong PANG,Wei ZHOU,Jian-song FANG,Guan-hua DU,,
来源:中国药理学与毒理学杂志 年份:2017
OBJECTIVE To find a promising candidate for anti-Alzheimer disease(AD)with multiple targets in multiple pathways.METHODS A series of classifiers were constructe...
In silico target fishing for the potential targets and molecular mechanisms of baicalein as an anti-
[会议论文] 作者:Li Gao,Jian-Song Fang,Xiao-Yu Bai,Dan Zhou,Ai-Lin Liu,Guan-Hua Du,
来源:全国老年性痴呆与相关疾病学术会议 年份:2013
The flavonoid baicalein has been proven effective in animal models of parkinsons disease, however, the potential biological targets and molecular mechanisms underlying the anti-parkinsonian action of...
,Anti-influenza effect and action mechanisms of the chemical constituent gallocatechin-7-gallate fro
[期刊论文] 作者:Chao Li,Lv-jie Xu,Wen-wen Lian,Xiao-cong Pang,Hao Jia,Ai-lin Liu,Guan-hua Du,
来源:中国药理学报(英文版) 年份:2018
Host cdc2-like kinase 1 (CLK1) is responsible for the alteative splicing of the influenza virus M2 gene during influenza virus infection and replication that ha...
DL0410 ameliorates cognitive disorder in SAMP8 mice by promoting mitochondrial dynamics and the NMDA
[期刊论文] 作者:Wen-wen Lian,Wei Zhou,Bao-yue Zhang,Hao Jia,Lv-jie Xu,Ai-lin Liu,Guan-hua Du,
来源:中国药理学报:英文版 年份:2021
Alzheimer’s disease (AD) is a worldwide problem and there are no effective drugs for AD treatment. Previous studies show that DL0410 is a multi-target, anti-AD agent. In this study, we investigated the therapeutic effect of DL0410 and its ......
[期刊论文] 作者:Xue Han,Xin Ji,Xuan Ma,Jun-Ling Liu,Zhen-Yu He,Wei Chang,Fei Tang,Ai-Lin Liu,
来源:环境科学学报(英文版) 年份:2020
Changes in water quality from source water to finished water and tap water at two conventional drinking water treatment plants (DWTPs) were monitored.Beside the...
[期刊论文] 作者:Wei Zhou,Wen-wen Lian,Rong Yan,Hao Jia,Lv-jie Xu,Lin Wang,Ai-lin Liu,Guan-hua Du,
来源:中国药理学报(英文版) 年份:2020
At present,few available drugs can be used to either improve pathological features or prevent the progression of Alzheimer’s disease (AD).DL0410 ((1,1’-([1,1...
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