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[会议论文] 作者：Alan Prem Kumar,
来源：2011第四届世界癌症大会 年份：2011
Mortality from breast cancer is almost entirely the result of invasion and metastasis of neoplastic cells; therefore, understanding gene products involved i...
Repression of Mn-superoxide Dismutase Expression by PPARγ Activation is a Potential New Approach for
[会议论文] 作者：Alan Prem Kumar,
来源：(BITs 3rd Annual World Cancer Congress-2010, Breast Cancer C 年份：2010
An approach to inhibit proliferation and increase cell death in breast cancer cell lines has given hope for the development of a new class of anticancer drugs.These new class of drugs are activators o...
Tumor-specific Regulation of MnSOD: Towards Targeted “Oxidation Therapy” in Estrogen Negative Breast
[会议论文] 作者：Alan Prem Kumar,
来源：BITs 3rd Annual World Cancer Congress-2012(2012第五届世界癌症大会) 年份：2012
Compelling evidence suggests that cancer cells are generally under reactive oxygen species (ROS) stress.As mitochondria respiration is the main source of ROS generation in the cells, MnSOD is of prime...
[会议论文] 作者：Alan Prem Kumar,
来源：2016第九届世界癌症大会 年份：2016
Resistance to chemotherapy offers limitations to the treatment of breast cancer.This has generated an increased interest in identifying new biomarkers to better predict drug responses among patients....
A Double Negative Loop Between ANXA1 and microRNA-196a Regulates Breast Cancer Proliferation and Tum
[会议论文] 作者：Yuan Yi,Alan Prem Kumar,Lina H.K.Lim,
来源：2016第九届世界癌症大会 年份：2016
In this study,we show that ectopic expression of microRNAmiR-196a enhances breast cancer cell proliferation while anti-miR-196a inhibits cell proliferationin vitro,and this is through the direct targe...
Role of Transcription Factor, AP2 in H2O2-mediated Repression of the Na+/H+ exchanger 1 (NHE-1) Gene
[会议论文] 作者：Sui Huay Chua,Alan Prem Kumar,Marie Veronique Clement,
来源：第14届国际自由基学术会议(The 14th Biennial Meeting of the Society for F 年份：2008
...
Role of Transcription Factor, AP2 in H2O2-mediated Repression of the Na+/H+ exchanger 1 (NHE-1) Gene
[会议论文] 作者：Sui Huay Chua,Alan Prem Kumar,Marie Veronique Clement,
来源：第14届国际自由基学术会议(The 14th Biennial Meeting of the Society for F 年份：2008
...
[期刊论文] 作者：Jing-wen ZHANG,Muthu K.SHANMUGAM,Amudha DEIVASIGAMANI,Alan Prem KUMAR,Kam Man HUI,Gautam SETHI,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Prostate cancer is one of the most commonly diagnosed cancers worldwide.Current therapies for metastatic prostate cancer are only marginally effective...
Suppression of signal transducer and activator of transcrlptlon-3 signaling cascade by zerumbone inh
[会议论文] 作者：Muthu K SHANMUGAM,Rajendran PERAMAIYAN,Feng LI,Siveen KODAPPULLY SIVARAMAN,Kwang Seok AHN,Alan Prem KUMAR,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
...
Suppression of signal transducer and activator of transcrlptlon-3 signaling cascade by zerumbone inh
[会议论文] 作者：Muthu K SHANMUGAM,Rajendran PERAMAIYAN,Feng LI,Siveen KODAPPULLY SIVARAMAN,Kwang Seok AHN,Alan Prem KUMAR,
来源：The 12th Meeting of the Asia Pacific Federation of Pharmacol 年份：2013
Aim: Signal transducer and activators of transcription 3 (STAT3) has been linked to the deregulated proliferation, survival, and angiogenesis in renal cell carcinoma (RCC).In this study we investigate...
[期刊论文] 作者：QIU,Jean Paul THIERY,Gautam SETHI,Patrick J.CASEY,Celestial T.YAP,Soo Chin LEE,Vinay TERGAONKAR,Alan Prem KUMAR,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To evaluate if RNA helicase DDX20,highly expressed in triple negative breast cancer(TNBC)cells,could serve as a surrogate marker for simvastatin treat...
[期刊论文] 作者：Wei Ney Yap,Frank Arfuso,Shreya Kar,Chao Wang,Wanpei Cai,Arunasalam M Dharmarajan,Gautam Sethi,Alan Prem Kumar,
来源：World Journal of Gastroenterology 年份：2015
Frequent activation of phosphatidylinositol-3 kinases(PI3K)/Akt/m TOR signaling pathway in gastric cancer(GC) is gaining immense popularity with identification...
Garcinol suppresses the growth of human hepatocellular carcinoma by inducing abrogation of STAT3 pho
[期刊论文] 作者：SHANMUGAM,Snehajyoti CHATTERJEE,Peramaiyan RAJENDRAN,Feng LI,Pari jat SENAPATI,KwongFai WONG,Alan Prem KUMAR,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Hepatocellular carcinoma(HCC)is the fifth most common malignancy worldwide and the third cause of global cancer mortality.Activation of signal transdu...
Ascochlorin overcomes chemoresistance and regulates the plasticity of doxorubicin induced EMT via mo
[期刊论文] 作者：Xiao-yun DAI,Kwang Seok AHN,Chulwon KIM,Muthu K SHANMUGAM,Feng LI,Ji-zhong SHI,Alan Prem KUMAR,Ling-zhi,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Doxorubicin-based therapy has been found to be not significantly effective for the treatment of advanced stage hepatocellular carcinomas(HCCs),which o...
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite do
[期刊论文] 作者：,Kodappully Sivaraman SIVEEN,Fan WANG,Tina H ONG,Ser Yue LOO,Mahadeva MM SWAMY,Somnath MANDAL,Alan Prem KUMAR,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE Platinum compounds such as cisplatin and carboplatin are frequently used as the first-line chemotherapy for the treatment of the head and neck squamou...
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