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[会议论文] 作者：Ben Shen,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
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[会议论文] 作者：Ben Shen,
来源：上海浦东免疫化学国际生物论坛 年份：2015
Inspired by the recent success of two ADCs (Adcetris(R) in 2011 and Kadcyla(R) in 2013), virtually every major pharmaceutical company with an oncology program n...
COMBINATORIAL BIOSYNTHESIS-NEW OPPORTUNITIES FOR MICROBIAL METABOLITE PRODUCTION AND TITER IMPROVEME
[会议论文] 作者：Ben Shen,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
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[会议论文] 作者：Guohui Pan,Ben Shen,
来源：第十一届全国化学生物学学术会议 年份：2019
Microbial genomes encode dramatic number of natural product biosynthetic gene clusters(BGCs),and the products of vast majority of these BGCs remain to be discovered....
[会议论文] 作者：Hui Ming Ge,Tingting Huang,Ben Shen,
来源：The 13th International Symposium on the Genetics of Industri 年份：2016
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REGIO-AND ENANTIOSPECIFIC INSTALLATION OF THE β-AMINO ACID MOIETY ONTO THE ENEDIVNE CORE OF THE ANTI
[会议论文] 作者：Shuangjun Lin,Steven G.Van Lanen,Ben Shen,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
C-1027 is an enediyne antitumor antibiotic composed of an apo-protein (CagA) and a reactive enediyne chromophore containing four distinct chemical moieties including an (S)-3-chloro-5-hydroxy-βtyrosin...
[会议论文] 作者：ZHANG Tuo,HE Ben,SHEN Ling-hong,JIN Shu-xuan,
来源：第11届中国介入心脏病学大会 年份：2013
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Functional Characterization of TtnM as FeⅡ-and α-KG-Dependent Hydroxylase in Tautomycetin Biosynthes
[会议论文] 作者：Dong-Hui Yang,Dong Yang,Ming Ma,Ben Shen,
来源：世界中医药学会联合会中药化学专业委员会第五届学术年会暨蒙医药论坛 年份：2016
Tautomycin (TTN) is a polyketide possessing potent anticancer activity due to its selective inhibitions against protein phosphatases (PPs) PP-1 and PP-2A.The 3R-hydroxy group in the dialkylmaleic anhy...
Staurosporine produced by marine-derived actinomycete Streptomyces roseoflavus MB-97 isolated from c
[会议论文] 作者：Jiangchun Hu,Nan Wang,Delin Xue,Shujin Wang,Jianhua Ju,Ben Shen,
来源：13th International Biotechnology Symposium and Exhibition(第1 年份：2008
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[会议论文] 作者：Xiangwei Gao,Ji Wan,Botao Liu,Ben Shen,Zhengping Xu,Shu-Bing Qian,
来源：华东六省一市生物化学与分子生物学学会2014年学术交流大会暨浙江省第十一届学会会员代表大会 年份：2014
Cells have evolved exquisite mechanisms to fine-tune the rate of protein synthesis in response to nutrient starvation, including alternative translation ini...
Staurosporine produced by marine-derived actinomycete Streptomyces roseoflavus MB-97 isolated from c
[会议论文] 作者：Jiangchun Hu,Jianhua Ju,Nan Wang,Delin Xue,Shujin Wang,Ben Shen,
来源：13th International Biotechnology Symposium and Exhibition(第1 年份：2008
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Improvement of platensimycin and platencin production in Streptomyces platensis and their activities
[会议论文] 作者：YongHuang,Xiangcheng Zhu,Yanwen Duan,Nan Ren,Jun Shi,Ling Liu,Ben Shen,
来源：第二届中国放线菌生物学与产业化研讨会 年份：2014
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Improvement of platensimycin and platencin production in Streptomyces platensis and their activities
[会议论文] 作者：YongHuang,Nan Ren,Xiangcheng Zhu,Jun Shi,Ling Liu,Ben Shen,Yanwen Duan,
来源：第二届中国放线菌生物学与产业化研讨会 年份：2014
Platensimycin (PTM) and platencin (PTN),isolated from several strains of Streptomyces platensis,are potent antibiotics against multi-drug resistant bacteria.Rec...
[会议论文] 作者：董廖斌,Jeffrey D.Rudolf,黄勇,K.N.Houk,段燕文,Ben Shen,
来源：第十一届全国化学生物学学术会议 年份：2019
平板霉素和平板素是从土壤链霉菌中发现的两种强效萜类抗生素，具有独特的抑制细菌脂肪酸合酶活性。[1]含有硫代羧酸基团的天然产物仅有三例报道，报告人从平板霉素高产菌中意外地获得含有硫代羧酸基团的硫代平板霉素和硫代平板素，[2]并确定了平板霉素和平板素是硫代......
,Alternative method for site-directed mutagenesis of complex polyketide synthase in Streptomyces alb
[期刊论文] 作者：Danfeng Song,Jane Coughlin,Jianhua Ju,Xiufen Zhou,Ben Shen,Chunhua Zhao,Zixin Deng,
来源：生物化学与生物物理学报（英文版） 年份：2008
Sequence analysis of oxazolomycin (OZM) biosynthetic gene cluster from Streptomyces albus JA3453 revealed a gene,ozmH, encoding a hybrid polyketide and non-ribo...
NEW ERYTHROMYCIN CONGENERS AND LINEAR POLYKETIDES ACTINOPOLYSPORA FROM A NEW HALOPHILIC ACTINOMYCETE
[会议论文] 作者：Li-Xing Zhao,Sheng-Xiong Huang,Shu-Kun Tang,Wen-Jun Li,Li-Hua Xu,Cheng-Lin Jiang,Yanwen Duan,Ben Shen,
来源：15th International Symposiium on the Biology of Actinomycete 年份：2009
In course of seeking novel bioactive compounds from extremophilic actinomycetes.two new erythromycin congeners erythronolides H (1) and 1 (2).three new linear polyketides actinopolysporins A-C (3-5),a...
[会议论文] 作者：Lin Qiu,Kai Tian,Lin Jiang,Hu Yang,Xiangcheng Zhu,Ben Shen,Yanwen Duan,Yong Huang,
来源：手性中国2016学术研讨会 年份：2016
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[会议论文] 作者：Lin Qiu,Kai Tian,Jian Pan,Lin Jiang,Hu Yang,Xiangcheng Zhu,Ben Shen,Yanwen Duan,Yong Huang,
来源：中国化学会第十一届全国天然有机化学学术会议 年份：2016
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TIMI myocardial perfusion frame count by angiography:a novel method to predict incomplete resolution
[会议论文] 作者：QIAO Zhi-qing,ZHAO Hang,PU Jun,DING Song,HE Ben,SHEN Xue-dong,SONG Wei,DU Yong-ping,SHEN Jie-yan,JIN,
来源：中国介入心脏病学大会(CIT2012) 年份：2012
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TIMI myocardial perfusion frame count by angiography: a novel method to predict incomplete resolutio
[会议论文] 作者：QIAO Zhi-qing,ZHAO Hang,PU Jun,DING Song,HE Ben,SHEN Xue-dong,SONG Wei,DU Yong-ping,SHEN Jie-yan,JIN,
来源：第11届中国介入心脏病学大会 年份：2013
Background TIMI Myocardial Perfusion Frame Count (TMPFC) developed by our medical center is a novel technique using coronary cine-angiography for quantifying the filling and clearance of contrast agen...
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