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[会议论文] 作者：Dik-Lung Ma,
来源：BCEIA2013第十五届北京分析测试学术报告会(分析仪器应用技术报告会) 年份：2013
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[会议论文] 作者：Dik-Lung Ma,
来源：The 12th International Symposium on Applied Biological Chemi 年份：2013
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[会议论文] 作者：Dik-Lung Ma,
来源：第十六届北京分析测试学术报告会 年份：2015
Enzymes are critically involved in maintaining normal cellular physiology throughthe catalysis of highly specific and tightly regulated chemical reactions....
Identification of a natural product-like STAT3 dimerization inhibitor by structure-based virtual scr
[期刊论文] 作者：Li-juan LIU,Ka-Ho LEUNG,Daniel Shiu-Hin CHAN,Dik-Lung MA,Chung-Hang LEUNG,,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To apply molecular docking techniques to identify STAT3 inhibitors from a database of over 90 000 natural product and natural product-like compounds.M...
[期刊论文] 作者：Ting LI,Xiao-huang XU,Zheng-hai TANG,Ya-fang WANG,Chung-hang LEUNG,Dik-lung MA,Xiu-ping CHEN,
来源：中国药理学报（英文版） 年份：2015
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[会议论文] 作者：Ka-Ho Leung,Daniel Shiu-Hin Chan,Yitao Wang,Dik-Lung Ma,Chung-Hang Leung,Hai-Jing Zhong,Li-Juan Liu,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
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[会议论文] 作者：Hai-Jing Zhong,Li-Juan Liu,Ka-Ho Leung,Daniel Shiu-Hin Chan,Yitao Wang,Dik-Lung Ma,Chung-Hang Leung,
来源：第十四届全国中药和天然药物学术研讨会暨第十三届中药全球化联盟大会 年份：2014
Virtual screening has recently emerged as a powerful technique to identify potential drug candidates against specific biomolecular targets, such as enzymes or protein receptors.Virtual screening can d...
Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-te
[会议论文] 作者：Zheng-Hai Tang,Xiu-Ping Chen,Ting Li,Jin-Jian Lu,Le-Le Zhang,Yi-Tao Wang,Jia-Hong Lu,Chung-Hang Leung,Dik-lung Ma,
来源：第四届广州国际肿瘤学会议 年份：2015
Glycerrhetinic acid(GA),one of the main bioactive constituents of Glycyrrhiza uralensis Fisch,presents anti-cancer effects to various cancer cells....
Glycyrrhetinic acid induces cytoprotective autophagy via the inositol-requiring enzyme 1α-c-Jun N-te
[会议论文] 作者：Zheng-Hai Tang,Le-Le Zhang,Ting Li,Jia-Hong Lu,Chung-Hang Leung,Dik-lung Ma,Xiu-Ping Chen,Hu-Lin Jiang,
来源：第四届广州国际肿瘤学会议 年份：2015
Glycerrhetinic acid(GA),one of the main bioactive constituents of Glycyrrhiza uralensis Fisch,presents anti-cancer effects to various cancer cells....
Platycodin D induces apoptosis and triggers an extracellular signal-regulated kinase and c-Jun N-ter
[会议论文] 作者：Ting Li,Xiao-Huang Xu,Zheng-Hai Tang,Ya-Fang Wang,Chung-Hang Leung,Dik-lung Ma,Xiu-Ping Chen,Yi-Tao Wang,
来源：第四届广州国际肿瘤学会议 年份：2015
Platycodin D(PD),the main saponin isolated from the Chinese herb Platycodon Radix,exhibits potential anticancer activity.Here we sought to evaluate the anticancer potential of PD both in vitro and in...
[会议论文] 作者：Si-Yuan PAN,Kam-Ming KO,Shu-Feng ZHOU,Si-Hua GAO,Dik-Lung MA,Shuo-Feng ZHANG,Zhi-Ling YU,Jian-Ning SUN,
来源：第二届世界天然药物和传统药物药理学学术会议 年份：2012
The low success rate, despite a huge capital investment, has made the research and development of conventional drugs very costly.Over the past few decades, researchers have focused on drug discovery f...
[期刊论文] 作者：Li-juan LIU,Ka-Ho LEUNG,Sheng LIN,Daniel Shiu-Hin CHAN,Dewi SUSANTI,Wei-dong RAO,Philip Wai Hong CHAN,Dik-Lung MA,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To employ pharmacophore modeling to identify a TACE inhibitor from an inhouse database of 66 organic compounds.METHODS To identify the common features...
[期刊论文] 作者：Dik-Lung MA,Daniel Shiu-Hin CHAN,Guo WEI,Hai-jing ZHONG,Hui YANG,Lai To LEUNG,Elizabeth A.GULLEN,Pauline,
来源：中国药理学与毒理学杂志 年份：2015
OBJECTIVE To utilize a structure-based lead optimization approach to generate novel natural product-like typeⅡ inhibitors of JAK2 using the DOLPHIN protocol.ME...
[期刊论文] 作者：Joshua William Boyle,Chung-Nga Ko,Wu Zeng,Vincent Kam Wai Wong,Jian-Bo Wan,Philip Wai Hong Chan,Dik-Lung Ma,
来源：药学学报（英文版） 年份：2019
We report in this study the identification of a natural product-like antagonist (1a) of Vps34 as a potent autophagy modulator via structure-based virtual screen...
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