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[学位论文] 作者:Elsayed Metwally Mahmoud Metwally,
来源:北京工业大学 年份:2011
Calpain是一类胞质半胱氨酸蛋白酶,与多种发育进程、局部脑缺血损伤和阿尔兹海默症等神经元变性有关。Calpain的蛋白水解活性依赖于Ca2+,但其活性是如何被调控的目前尚不清楚。...
[会议论文] 作者:Elsayed Metwally,Guoli Zhao,Yong Q.Zhang,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
The efficiency of neurotransmission is determined by the level of neurotransmitter receptors at the postsynaptic densities.However,the molecular mechanism by which the level of neurotransmitter recept...
Ttm50 facilitates calpain activation by anchoring it to calcium stores and increasing its sensitivit
[期刊论文] 作者:Elsayed Metwally,Guoli Zhao,Qifu Wang,Yong Q.Zhang,
来源:细胞研究(英文版) 年份:2021
Calcium-dependent proteolytic calpains are implicated in a variety of physiological processes,as well as pathologies associated with calcium overload.However,th...
Homeostatic regulation of glutamate receptor subtypes ⅡA and ⅡB at Drosophila neuromuscular junction
[会议论文] 作者:Kai Zhao,Lu Zhao,Elsayed Metwally Mahmoud,Yong Q.Zhang,
来源:The 6th FAONS Congress and 11th Biennial Conference of CNS(第 年份:2015
The majority of excitatory synapses in the mammalian brain are glutamatergic.For the normal functioning of excitatory synapses,different types and subtypes of glutamate receptors(GluRs)have to be accu...
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