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Boron-based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Canc
[会议论文] 作者：Guangdi Wang,
来源：2013第三届内分泌与代谢大会暨2013第二届糖尿病大会 年份：2013
Tamoxifen remains the first line therapy for estrogen receptor positive (ER+) breast cancer.However, polymorphisms of the gene encoding P450 2D6 could result in no protein expression or no CYP2D6 enzy...
[会议论文] 作者：Guangdi Wang,
来源：BIT`s 2nd Annual World Congress of Endobolism-2012(2012第二届内分 年份：2012
PURPOSE: To determine the structural requirements for the transformation from estrogenic to anti-estrogenic compounds in a series of daidzein derivatives.DESIGN METHODS: A series of daidzein analogues...
In Vitro Metabolism of Indomethacin Morpholinylamide (BML-190), An Inverse Agonist for the Periphera
[会议论文] 作者：Guangdi Wang,
来源：2011年第一届内分泌与代谢大会 年份：2011
The in vitro metabolism of an inverse agonist of the peripheral cannabinoid receptor (CB2), indomethaein morpholinylamide (BML-190), has been characterized using rat liver microsomal incubation.BML-19...
Regional distribution of endocrine disrupting chemicals and pharmaceuticals in Mississippi River Del
[会议论文] 作者：Guangdi Wang,Peng Ma,Qiang Zhang,John Lewis,
来源：环境毒理与环境化学国际学术研讨会——亚太分会2010年会(SETAC Asia/Pacific2010) 年份：2010
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[会议论文] 作者：Cui,Li Ma,Xin Gao,Danita Eatman,Minerva Garcia-Barrio,Mohamed A.Bayorh,Xiaodong Zhang,Jin Zou,Guangdi Wang,
来源：2015中国医师协会妇产科医师大会 年份：2015
Rationale: Current knowledge related to the association between obesity and inflammation states that obesity causes systemic low-grade inflammation.Objective: C-reactive protein (CRP) has been widely...
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