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Design,Synthesis and Biological Evaluation of Novel Derivatives of Laropiprantas Potent Prostaglandi
[会议论文] 作者:Haiping Zhou,Guangping Dong,Lijun Xiao,YungenXu,
来源:第九届IUPAC化学生物学国际研讨会暨第八届世界华人药物化学研讨会 年份:2012
Laropiprant,approved by the European Medicines Agency(EMA) in 2008,is used in combination with nicotinic acid to reduce blood cholesterol.Laropiprant itself,as a prostaglandin D2 receptor 1(DP1) antag...
[会议论文] 作者:Guangming Liu,Yongshou yang,Guangping Dong,Huai Xiao,
来源:农作物废弃物功能成分筛选暨首届芒果苷研究国际研讨会 年份:2009
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Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferas
[期刊论文] 作者:Ayad A.Al-Hamashi,Dongxing Chen,Youchao Deng,Guangping Dong,Rong Huang,
来源:药学学报(英文版) 年份:2021
Protein arginine methyltransferases(PRMTs)have been implicated in the progression of many diseases.Understanding substrate recognition and specificity of individual PRMT would facilitate the discovery of selective inhibitors towards future ......
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